MCQs:Hepatitis B serology

Here are some fairly straightforward questions on Hepatitis B serology. Try them and then click the link at the bottom of the page for answers and brief explanations.


1) Most positive HBsAg results picked up on ante-natal screening represent chronic infection? T/F

2) IgM Anti-HBc can be used to differentiate acute from chronic Hepatitis B infection? T/F

3) A patient with negative HBeAg will always have a low HBV viral load? T/F

4) Anti-HBc is usually positive in chronic Hepatitis B infection? T/F

5) A patient who has had acute Hepatitis B infection in the past and has cleared the virus, will have positive anti-HBc and anti-HBs? T/F

6) Hepatitis B vaccination induces a strong anti-HBc response? T/F

7) The incubation period after exposure to Hepatitis B virus is approximately 1 week? T/F

8) Expectant mothers who are HBsAg +ve may be candidates for anti-viral treatment? T/F

9) Patients who are anti-HBc +ve, but negative for HBsAg and anti-HBs. This can represent a range of scenarios, the most common being resolved acute infection? T/F

10) Patients who are HBsAg +ve and also anti-HBe +ve are not infective to others? T/F


Click here for the answers and brief explanations.

4 thoughts on “MCQs:Hepatitis B serology

  1. Regarding Q9. The CDC states that resolving acute infection is the 4th most common cause for who are anti-HBc +ve, but negative for HBsAg and anti-HBs. Most common being resolved distant infection.

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