Monthly Archives: July 2017

“The Addicted Microbiologist”

Up until recently I used to check my work emails on my I-phone every 20-30 minutes throughout the evening, sitting at home on the couch.

Not only evenings, but weekends and holidays as well. It was all a bit sad really.

It wasn’t for any particular reason, it was more like an automatic reflex. And if I went a prolonged period without checking them, I started to get a bit edgy and irritable…

I was addicted.

I have always had an addictive personality, and I have been addicted to many different things throughout my life. But I never thought I would be addicted to work emails however.

Wow, I am getting old…

So on realising I had a problem, I decided to do something about it.

About 6 months ago, I went cold turkey.

I didn’t just switch the work emails off from my smartphone, I completely uninstalled the server, so as to resist temptation.

So now when I leave the laboratory I don’t check my emails again until I am back in the laboratory.

And sure enough,  the sky hasn’t fallen. The emails sit there quite happily, waiting patiently for me to look at them. And when I do get round to looking at them the next (working) day, there is a little pile of them which I can then deal with somewhat ruthlessly, and certainly much quicker than answering them “individually” at periodic intervals.

Apart from addiction there is another good reason for not checking emails out of normal working hours. The majority of incoming emails are from people looking for something, a bit of your time, a bit of your expertise, a bit of your life…

Follow your own agenda, not other people’s.

March to the beat of your own drum…

I have five children, and a sixth on the way. I now have better things to do in the evening, like changing nappies!

But checking work emails at home is now a thing of a past. Trust me, there is not much that cannot wait in the world of microbiology…

Michael

“Communication Breakdown”

We conducted a brief audit recently on blood culture identification, and in particular how long it took for a definitive identification result (by MALDI-TOF) to be relayed to the hospital clinicians.

Audits are great at demonstrating that you are not half as good as you think you are…

Our audit showed that it was taking anywhere (depending on which cohort was studied) between 8 and 16 hours from when the identification was released by the laboratory into the “result repository”, until the result was actually viewed by a clinician.

And at the weekends the time delay was even longer, up to a day.

Oops…

You can have the most sophisticated equipment in your laboratory, and we do…

You can have highly skilled and motivated staff members, and sure enough, we have them.

And you can also have one of the most progressive provincial microbiology laboratories in the world, and I like to think we have that as well.

But it all counts for nothing if we can’t communicate our results in a timely fashion.

Audit can be painful to perform, but highly informative in implementing best practice.

So back to the drawing board for us. Time to sit down and talk with the clinicians and work out a way to communicate results more quickly in order to optimise patient outcomes.

It’s good to talk.

Pre-analytical, peri-analytical and post-analytical phases. They all matter, and they all need to be addressed…

Michael

 

“Bacteriology Automation: Warts and all…”

Whether you are a microbiology student undertaking exams, a lab manager considering a business case, or a scientist wondering just what exactly the future holds, you need to know something about bacteriology automation.

We have now had the Kiestra TLA in place for 18 months at the lab where I work. It would be foolish to say it has all been plain sailing. Far from it. There have been breakdowns, computer malfunctions, and interfacing problems, particularly in the early days.

The learning curve is very steep.

But would I ever go back to traditional “manual” bacteriology processing? No way! In fact, I would go as far as to say that I would be very reluctant to ever work in a microbiology lab in the future that didn’t have automation of the bacterial culture process.

It would simply be a backward step…

With some great feedback from staff members (and expanding on a previous post), I have listed below an honest account as to what I think are the advantages and disadvantages of a bacterial automation system like Kiestra:

 

ADVANTAGES

  • Standardised incubation times: Personally I think this is one of the strongest advantages of the system. No matter when the plate was inoculated, the system will image the plate after a pre-set incubation time, and thus allow plate reading. This in turn will allow reduction in turnaround times for specimens. The old concept of Day 1, Day 2, etc. plate reading should disappear and be replaced by 1st reading, 2nd reading….
  • Plate Tracking: Each plate has a  comprehensive electronic audit trail attached to it, including when it was inoculated, incubated, imaged and read, and by whom. The audit trail is encyclopaedic, if not a little complex in nature.
  • Less menial tasks: Gets rid of finding appropriate plates for each sample, carrying the plates to and from the incubator, “putting up” of specimens, and other repetitive, manual tasks.
  • Better plate spreading: Automated spreading performed by machine will almost always succeed in better use of the whole agar plate and improved isolation of single colonies. It will also be a standardised procedure. Kiestra TLA uses the magnetic rolling bead method. It occasionally needs a bit of tweaking, but when it works, it is beautiful!
  • Less plate contamination: As the plate has less manual handling and less time spent with its lid off, the risk of plate contamination is almost certainly much reduced, which is very important for those “sterile site” specimens. A study in this area would make a nice research project for someone.
  • Storage of digital images of plates: Plates eventually deteriorate, images do not, and images can be stored to be viewed again at any stage in the future depending on how long you want to store them for. Great for presentations!
  • Less time out of the incubator: The plate goes straight into the incubator when it is inoculated, and essentially stays in the incubator whilst it is being examined. No hanging around and very little downtime. The advantage is twofold; shortened turnaround times, and a decreased chance of “losing” fastidious organisms.
  • Remote plate reading: The system should allow you to view the plate images from anywhere, including home. The possibility of microbiology scientists working from home in the near future is a real one.
  • Plate interpretation: This is still in the developmental stage but software is now available allowing rapid detection of plates with no growth, and (chromogenic)plates with colonies of a particular colour. Further development in such software will eventually lead to massive gains in efficiency.

 

DISADVANTAGES

  • Redundancy of staff: Whether staff members are made redundant or not due to the implementation of a system like Kiestra TLA, the simple fact is that this type of automation will get through (far) more specimens with less labour. Some (managers) might see this as an advantage, but from a people point of view it is a big downside. I personally find this aspect of automation very difficult to deal with.
  • Dependency on the automation: What happens if it breaks down? Because of the above, and because it is a complex operation, the consequences can be potentially serious if the system goes down. Fortunately as the Kiestra TLA is modular in nature, it is very unusual for the whole system to go down at once. We are also fortunate to have excellent engineering support at our lab.
  • Loss of ownership: Because the majority of the culture process is automated, staff members are less involved with the clinical sample from start to finish. This can lead to a loss of “ownership” of the sample.
  • Loss of continuity: Even with Kiestra TLA, there are still a few steps in the process that are still to be automated. Those steps are batched together in lists (e.g. MALDI-TOF spotting, susceptibility testing). Staff members are often only involved with one step in the whole culture process for any one patient sample. Continuity, which I regard as important, can therefore be lost…
  • More knowledge required: Not only do the staff now need to know about microbiology, they also need to know about Kiestra, how the system works, and how to troubleshoot any issues. Therefore a lot of new learning is required, as well as keeping up core knowledge in microbiology.

 

Change always comes with downsides as well as upsides.

But having said that, change is utterly inevitable, and I believe that Kiestra TLA or similar systems ( Biomeurieux, Copan Wasp) will be as ubiquitous as MALDI-TOFs in our clinical microbiology laboratories in 10 years time.

And if you understand both the pros and the cons of such systems before you start, it makes that change just a little bit easier…

Michael

A couple more posts coming on microbiology automation over the next week!